Synthesis of Optically Active Bicyclic Derivatives of Nitroimidazoles
نویسندگان
چکیده
Nitroimidazoles are characterized by a wide range of biological activity and many them used as therapeutics. Moreover, some bicyclic nitroimidazooxazoles show considerable potency against Mycobacterium tuberculosis. Some authors noticed that in the case chiral derivatives nitroimidazodihydrooxazoles, (R) form shows greater tuberculostatic than (S) enantiomer. This work describes procurement new 12 enantiomeric nitroimidazole.
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ژورنال
عنوان ژورنال: Compounds
سال: 2021
ISSN: ['2673-6918']
DOI: https://doi.org/10.3390/compounds1030013